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Endoscopy Report

Printed From: Barrett's Support Forum
Category: Barrett's Support Forum
Forum Name: General
Forum Discription: A place to just chat & introduce yourself
Printed Date: 07 Jul 2020 at 11:37am

Topic: Endoscopy Report
Posted By: MargaretO
Subject: Endoscopy Report
Date Posted: 14 Jun 2018 at 8:19am
Hi, this is my first post although I have been visiting this site for several after my first diagnosis of Barrett’s.

I was diagnosed in 2013 after suffering severe heartburn and reflux.After the endoscopy I was told I had a Hiatus Hernia and Barretts given an information sheet on it from the NHS, nobody fully explained it to me..

I had my repeat endoscopy in 2016 and received this report:-

Oesophageal biopsy...34cm, columnar mucosa and one of the fragments mucosa in continuity with the columnar mucus with under lying lamina proprietary containing mild mixed inflammatory cell infiltrate intestinal metaphysical is seen.

Biopsy 32cm...fragments of specialised gastric glandular mucosa with mild to moderate inflammatory cell infiltrate in the lamina proprietary.
Histlogical appearances are consistent with the clinical impression of Barrett’s. There is no evidence of dysphasia or malignancy.

Repeat endoscopy in Oct 2018 to check on mild inflammation.

It is difficult to understand and I asked my GP if he could explain it he did his best.

I have read that if there is no Intestinal Metaplasa this is a good finding.

It causes me stress from time to time and I am going through one of those times at the moment.

Any comments on this report would be very much appreciated.

Posted By: chrisrob
Date Posted: 14 Jun 2018 at 4:22pm
Hello Margaret and welcome to the forum.

Those endoscopy and biopsy reports can be a bit bewildering.

In UK, Barrett's is defined as columnar cells which may be gastric, or cardial, metaplasia or intestinal metaplasia. ie That means resembling the cells that line the stomach or the cells that line the intestines. The difference between gastric and intestinal metaplasia is that in the latter, they may find some small extra cells called goblet cells. We don't actually know the purpose of those cells and they may actually be present, but not seen, with gastric metaplasia.

Intestinal metaplasia is probably more likely to progress towards cancer (oesophageal adenocarcinoma) that gastric metaplasia, however progression risks are very small.

The good news is you have been identified and with regular medication and surveillance every few years, it is extremely unlikely your condition will progress to cancer. If any changes (dysplasia) are ever seen, you can have the Barrett's removed by ablation to prevent that happening.

You should find this book helpful - . It is a free fully researched and referenced encylopaedia about acid and reflux, their complications and management. (If you wish to send me a postal address, I can send you a printed copy.)

I don't know where in England you live but we have been attempting to build a nationwide Barrett's patient support network. If you visit Barrett's UK ( -
you may find a support group near you but will also find links to all reputable sources of information.

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Posted By: MargaretO
Date Posted: 14 Jun 2018 at 6:09pm
Thank you Chris most informative, I live in Lancashire not far from Manchester.

At first when Barretts was diagnosed I felt like I had been given a death sentence as not long before my diagnosis a very dear friend had been diagnosed with Barretts and within 2 weeks of his diagnosis it was confirmed he had cancer of the oesophagus. I am ok with it most of the time just every now and then I have a wobble and need information.

Posted By: chrisrob
Date Posted: 14 Jun 2018 at 6:27pm
Good luck, Margaret. We do hope the - Barrett's Manchester group gets established later this year as we already have a number of interested people, including Reg England, who may be contacted via - .
I have been in contact with Dr Rob Willert, the gastroenterologist at Manchester who will be helping ths launch. Unfortunately, the group's launch was postponed due to an accreditation process and backlogs but we hoe to progress this soon.

I am stepping down as chairman of Barrett's Wessex charity (that is setting up this network) but will continue to act as advisor to the different groups. If you'd like to be kept up to date with any progress on the Barrett's Manchester group, I can add your email to the contact list?

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Posted By: MargaretO
Date Posted: 14 Jun 2018 at 8:47pm
Yes please would you add me to the contact list. All the very best on your ‘Retirement’ from your Chairmanship. No doubt you can look back with pride at the progress which has been made and the advice and comfort you have given, Barretts is a very daunting diagnosis. Margaret

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