Hi Jackie,

As you have observed, it is unlikely your Barrett's will mutate to cancer. If you're in UK (with highest incidence worldwide), the risk of that happening is about 1 in 400 per year but those of us who know we have Barrett's are the lucky ones as we'll have regular medication that reduces that risk and regular surveillance every few years to look for early pre-cancerous changes (dysplasia) whence, if they were ever seen, could be removed by ablation.

Chest pains as you describe are not uncommon for refluxers. It's not from the Barrett's but could be from the reflux itself.
Running beside the esophagus as it passes through the hiatus hole in the diaphragm to the stomach, is the vagus nerve. A refluxing oesophagus can spasm and, impinging on that nerve, transmit signals that can appear to come from anywhere in the upper body: heart and shoulder blade are the most frequently reported areas.

Unfortunately, however good they are at reducing acid, the acid suppressant medications only do that. They do not reduce reflux; they just make it less damaging.

I have had so many heart tests over the years, I know mine's OK. But my father died of a heart attack when I was just a young teen so they take any chest pains seriously. I've had countless ECGs - including on treadmills, echograms etc and even wore an implanted heart monitor for a few years.

It is important heart problems are ruled out, as you have done. You can discuss with your GP the suggestion it could be from vagus nerve and see if there's any medication that could calm that response.

It is unlikely to be oesophageal cancer. The symptoms of that are different. Any developing tumour would cause swallowing problems instead.

Keep a diary of when these pains are most likely to occur and see if they follow eating in a particular way (eg larger portion than normal, rushed or slouching on the sofa).